Tweetie For Mac

TweetieTweetie features a very simple and fast interface that mimic Twitter’s Web site functionality. You can view tweets from people you are following or just replies to you. You can also view direct messages, sorted by the sender. Searches are the fourth type of screen you can bring up.
The best thing about Tweetie is it is fast and clean. It is a native Mac application, not relying on Adobe AIR. It doesn’t include many advanced features like other clients, but you can watch tweets roll in live. There is a paid $15 version and a free version that will show advertising.
Get Tweetie.